Celiac Immunochromatographic (Lateral flow) Test
The BIOHIT Celiac Quick Test is an immunochromatographic assay designed to qualitatively detect anti-tissue transglutaminase (tTG) antibodies (IgA, IgG, IgM). This highly specific test is for capillary (finger prick) whole blood samples and can be used by healthcare providers at the point of care.
The sample is applied to the lateral flow test cassette along with a buffer solution immediately after sample collection, and the results become readily visible within ten minutes.
This test is well-suited for near-patient testing, catering to the needs of general practitioners, gastroenterologists, dieticians, and pharmacists. It proves beneficial in investigating symptoms resembling irritable bowel syndrome (IBS) and aids in the identification of celiac disease in both children and adults.
How to Test for Celiac Disease
The conclusive diagnosis of celiac disease (CD) relies on distinctive histological alterations observed in intestinal biopsies. Nevertheless, serological tests like the Celiac Quick Test provide cost-effective and less intrusive diagnostic methods that may negate the necessity for biopsies. In individuals with CD, autoantibodies are generated against endomysium, a constituent of smooth muscle tissue. The primary antigen for anti-endomysium antibodies is tissue transglutaminase (tTG). Human tTG is utilised in serology tests to identify anti-tTG antibodies from a serum sample, forming the foundation for a highly precise celiac screening examination. Such tests prove especially advantageous for paediatric patients, where the threshold for performing upper gastrointestinal endoscopy is higher.