Identify and characterise dysbiosis
The GA-map® Dysbiosis Test Lx is a pioneering clinical test that utilises faecal specimens to identify and characterise dysbiosis, an imbalance in the gut microbiota linked to several health conditions such as inflammatory bowel disease, irritable bowel syndrome, and other autoimmune disorders. Dysbiosis occurs when there is a permanent or transient imbalance in the gut microbiota composition due to an increase in potentially harmful bacteria and/or a decrease in commensal bacteria. This imbalance can lead to dysfunction of the intestinal immune system and trigger a variety of gastrointestinal disorders.
The test employs 48 highly specific probes that target pre-determined multiplex targets and exploit single nucleotide differences in the 16S rRNA gene – a gene common to all bacteria. By leveraging cutting-edge high-throughput technology, the test can identify over 300 species of bacteria at different taxonomic levels in one reaction, making it an efficient and accurate diagnostic tool for characterising the microbiota.